Why the study?
Although the mechanisms of skeletal muscle fiber development have been studied for decades, many aspects of this process remain not completely understood.
The embryonic chick primary muscle culture is a robust in vitro model for studying skeletal myogenesis due to its autonomous myogenic program and high level of differentiation compared to cell lines.
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May enhance in vitro myogenesis research; leaves open validation against mammalian or human models.
Costa et al. (2021) studied this question.
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