Population
Dogs (normal and chronic sympathectomized)
Design
Preclinical
Authors
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Caution advised when citing flow-consumption correlations as regulatory evidence; leaves open distinct rate- and extraction-linked mechanisms in normal versus sympathectomized hearts.
High correlations between coronary blood flow and myocardial oxygen consumption in literature may be spurious due to shared mathematical elements, cautioning against interpreting them as functional relationships.
Scott et al. (1959) studied this question.
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