Successful treatment of atrial tachycardia-induced cardiomyopathy with pilsicainide

133 initial survivors of a first myocardial infarction who received thrombolytic treatment, mean age 62, 70% male, UK-based. Key inclusion: first MI, survival to three days, received thrombolysis. Key exclusions: second or subsequent MI, poor echocardiography window, unable to give consent.

Measurement of brain natriuretic peptide (BNP) concentrations and transthoracic echocardiography at 3 to 7 days (early) and 2 months (late) post-myocardial infarction.

Wall motion index < 1.2, end systolic left ventricular volume index, and mortality at one year.surrogate