November 1, 1996Journal of Hypertension
Left ventricular mass is linked to cardiac noradrenaline in normotensive and hypertensive patients
Population
39 patients without coronary artery disease, including 25 with arterial hypertension, 7 normotensive…
Design
Cross-sectional
Authors
Discussion
Loading...
Member takes
Implication
Sympathetic activity may promote LV hypertrophy beyond BP; cross-sectional data leave causality and therapeutic implications open.
Structured PICO
P
Population
39 patients without coronary artery disease (excluded by cardiac catheterization), including 25 with arterial hypertension (5 with left ventricular hypertrophy [HT + LVH], 20 with normal left ventricular mass [HT - LVH]), 7 normotensive patients with hypertrophic cardiomyopathy (HCM), and 7 normotensive controls.
O
Outcome
Correlation between left ventricular mass and cardiac noradrenaline releasesurrogate
Increased left ventricular mass in both normotensive and hypertensive patients is closely coupled to increased cardiac sympathetic activity, independent of arterial blood pressure.
Cite This Study
Kelm et al. (1996) studied this question.