Key result
Central sympathetic activation was significantly positively correlated with left ventricular mass index in hypertensive patients with and without left ventricular hypertrophy (r≥0.76, P<0.0001).
Population
73 subjects including 24 patients with uncomplicated and untreated essential hypertension without left…
Design
Cross-sectional
Authors
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Cross-sectional correlation warrants no practice change; leaves open whether sympathetic inhibition reduces LV mass in hypertension.
Cross-Sectional (n=73)
Effect estimate: r ≥ 0.76
p-value: p=<0.0001
Central sympathetic activation is significantly correlated with left ventricular mass index in patients with essential hypertension, supporting its role in the development of left ventricular hypertrophy.
Burns et al. (2007) conducted a cross-sectional in Essential hypertension (n=73). Central sympathetic drive vs. Normal control subjects was evaluated on Correlation between sympathetic activity and left ventricular mass index (r ≥ 0.76, p=<0.0001). Central sympathetic activation was significantly positively correlated with left ventricular mass index in hypertensive patients with and without left ventricular hypertrophy (r≥0.76, P<0.0001).
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