Key result
Prehypertension was associated with higher left ventricular mass index compared to normotension, and central BP was not superior to brachial BP for this association.
Why the study?
Is prehypertension associated with increased left ventricular mass index compared to normotension, and does central blood pressure correlate better with LVMI than brachial blood pressure?
Cross-Sectional (n=65)
Is prehypertension associated with increased left ventricular mass index compared to normotension, and does central blood pressure correlate better with LVMI than brachial blood pressure?
Prehypertension is independently associated with increased left ventricular mass index, indicating early cardiovascular target organ damage, with brachial and central BP showing similar correlations.
Answers are grounded in this paper and cite their sources.
Signals early LV remodeling in prehypertension; cross-sectional data leaves open causal effects and any added value of central over brachial BP.
Introduction. The purpose of this observational cross-sectional study was to assess left ventricular mass (LVM) in prehypertensive individuals in comparison to normotensives and to determine if central blood pressure (BP) correlates better with LVM index (LVMI) than brachial BP. Methods and Result. Brachial and central BP measurements were completed at first visit and at 4 weeks in 65 healthy volunteers who were at least 40 years old and not on medication. Subjects were divided into two groups of normotensives and prehypertensives based on JNC-7 criteria and LVM was obtained using cardiac magnetic resonance imaging. Prehypertensives had significantly higher LVMI compared to normotensives (P < 0.01). Brachial and central BP also both positively correlate with LVMI (r = 0.460, P < 0.01; r = 0.318, P = 0.012, resp.) in both groups and neither method was superior to the other. After multivariate regression analysis and adjusting for cardiovascular risk factors, prehypertension remained an independent determinant of LVM. Conclusion. Prehypertension is associated with cardiovascular target organ damage, and central BP was not superior to brachial BP or vice versa for association with LVMI.
No takes yet. Share an insight, caveat, or question.
Mousa et al. (2015) conducted a cross-sectional in Prehypertension (n=65). Prehypertension vs. Normotension was evaluated on Left ventricular mass index (LVMI) (p=<0.01). Prehypertension was associated with higher left ventricular mass index compared to normotension, and central BP was not superior to brachial BP for this association.
Synapse has enriched 10 related papers. Consider them for comparative context: