Why the study?
Does anti-hypertensive treatment normalize capillary rarefaction in patients with essential hypertension compared to normotensive subjects?
Population
47 subjects, comprising 28 well-controlled essential hypertensive patients and 19 normotensive subjects.
Comparison
Anti-hypertensive treatment vs Normotensive subjects
Design
Cross-sectional
Authors
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Persistent rarefaction in treated hypertension may not normalize with BP control alone; leaves open whether microvascular-targeted therapies improve outcomes.
Does anti-hypertensive treatment normalize capillary rarefaction in patients with essential hypertension compared to normotensive subjects?
Well-controlled essential hypertension is associated with persistent microvascular rarefaction and reduced red blood cell velocity despite anti-hypertensive therapy.
Penna et al. (2008) studied this question.
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