Why the study?
Heart failure confers potentially negative effects on the brain and autonomic nervous system, and measuring cerebral tissue oxygen saturation may aid in understanding these effects.
Does compensated heart failure affect cerebral tissue oxygen saturation at rest and during orthostatic challenge compared to controls?
Population
61 HF patients (NYHA class I-III) and 60 controls
Comparison
Compensated HF patients vs controls
Design
Observational comparative study
Authors
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Hypothesis-generating for cerebral hypoxia in compensated HF; leaves open links to cognition and prognosis.
Does compensated heart failure affect cerebral tissue oxygen saturation at rest and during orthostatic challenge compared to controls?
Compensated heart failure is associated with impaired cerebral tissue oxygenation both at rest and during orthostatic stress, which may have implications for cognitive function and prognosis.
Kharraziha et al. (2020) studied this question.
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