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February 1, 1999Clinical Physiology

Reproducibility of the alterations in circulation and cerebral oxygenation from supine rest to head‐up tilt

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Key result

Head-up tilt testing produces reproducible changes in SV, MAP, and cerebral oxygenation versus supine rest.

  • n=10

Why the study?

Are the alterations in circulation and cerebral oxygenation from supine rest to head-up tilt reproducible in healthy individuals?

Population

10 healthy individuals

Comparison

Head-up tilt testing (70 degrees for 10 minutes) vs Supine rest (10 minutes)

Design

Other

Follow-up

Two different days

Authors

HHoutmanCColierHHopman

Discussion

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Member takes

Overview

Reproducibility of these measures in healthy subjects supports their use in research protocols; does not yet inform clinical practice.

Study Design

Type

Observational (n=10)

Structured PICO

Are the alterations in circulation and cerebral oxygenation from supine rest to head-up tilt reproducible in healthy individuals?

P
Population
10 healthy individuals who underwent supine rest and head-up tilt testing on two different days.
E
Exposure
Head-up tilt testing (70 degrees for 10 minutes)
C
Comparator
Supine rest (10 minutes)
O
Outcome
Reproducibility of alterations in stroke volume (SV), mean arterial pressure (MAP), oxygenated ([O2Hb]) and deoxygenated haemoglobin ([HHb]) concentration in cerebral tissuesurrogate

Measurements of MAP by Portapres, SV by Modelflow, and HHb by NIRS during head-up tilt testing are reproducible and suitable for follow-up studies.

Cite This Study

Houtman et al. (1999) conducted an observational in Healthy (n=10). Head-up tilt (HUT) vs. Supine rest (SUP) was evaluated on Reproducibility of alterations in stroke volume, mean arterial pressure, and cerebral oxygenation. Head-up tilt testing produced reproducible changes in stroke volume, mean arterial pressure, and deoxygenated hemoglobin concentration compared to supine rest in healthy individuals.

synapsesocial.com/papers/6aa4cdd1ac77d5296f2bcc1ehttps://doi.org/10.1046/j.1365-2281.1999.00159.x
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