Prognostic influence of mitral regurgitation prior to a first myocardial infarction
Why the study?
Does pre-existing mitral regurgitation worsen long-term prognosis in patients suffering a first acute myocardial infarction?
Population
68 consecutive patients with a first acute myocardial infarction and an echocardiographic study before AMI…
Comparison
Presence of pre-AMI degenerative mitral… vs Absence of pre-AMI mitral regurgitation
Design
Cohort
Follow-up
Median survival 912 days (Group 1) and 1423 days (Group 2)
Authors
Discussion
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Member takes
Implication
Pre-existing mitral regurgitation may identify higher-risk post-AMI patients; leaves open whether intervention improves outcomes.
Structured PICO
Does pre-existing mitral regurgitation worsen long-term prognosis in patients suffering a first acute myocardial infarction?
P
Population
68 consecutive patients with a first acute myocardial infarction (AMI) and an echocardiographic study before AMI (<3 months), mean age 75.5, 55.9% male. Inclusion: confirmed degenerative changes at the level of the mitral valve. Exclusion: any other cause of mitral regurgitation.
I
Intervention
Presence of pre-AMI degenerative mitral regurgitation
C
Comparator
Absence of pre-AMI mitral regurgitation
O
Outcome
Short- and long-term prognosis (survival and post-AMI evolution)hard clinical
Pre-existing degenerative mitral regurgitation is an independent prognostic marker for worse long-term survival following a first acute myocardial infarction.
Cite This Study
Zamorano et al. (2004) studied this question.