Why the study?
Does the combination of low-dose aspirin with antithrombotic drugs or NSAIDs aggravate hemorrhagic gastroduodenal ulcer bleeding in elderly patients compared to LDA monotherapy?
Does the combination of low-dose aspirin with antithrombotic drugs or NSAIDs aggravate hemorrhagic gastroduodenal ulcer bleeding in elderly patients compared to LDA monotherapy?
Combining low-dose aspirin with other antithrombotics or NSAIDs increases the severity of gastroduodenal ulcer bleeding in elderly patients, whereas advanced age alone does not worsen outcomes on LDA monotherapy.
Caution with LDA combinations in ulcer patients; leaves open age as independent risk on monotherapy.
AIM: To determine the clinical characteristics of elderly patients of hemorrhagic gastroduodenal ulcer on low-dose aspirin (LDA) therapy. METHODS: infection, presence/absence of underlying disease, and percentage of severe cases. RESULTS: = 0.985). CONCLUSION: A combination of LDA with antithrombotic drugs or non-steroidal anti-inflammatory drugs (NSAIDs) contributes to aggravation. And advanced age is not an aggravating factor when LDA monotherapy is used.
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Fukushi et al. (2018) studied this question.
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