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January 24, 2014European Heart Journal

Long-term survival after alcohol septal ablation for hypertrophic obstructive cardiomyopathy: a comparison with general population

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Why the study?

Does alcohol septal ablation result in long-term survival comparable to the general population in highly symptomatic patients with HOCM?

Population

178 highly symptomatic, consecutive patients with hypertrophic obstructive cardiomyopathy, mean age 58 ± 12…

Comparison

Alcohol septal ablation (ASA) vs Age- and sex-comparable general population

Design

Cohort

Follow-up

4.8 years (IQR 2.1-7.5)

Authors

JVJosef VeselkaUniversitat Autònoma de BarcelonaJKJan KrejčíMasaryk UniversityPTPavol TomašovKrajská Nemocnice Liberec

Discussion

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Implication

Supports ASA consideration in symptomatic HOCM; leaves open confirmation of survival equivalence in randomized trials.

Structured PICO

Does alcohol septal ablation result in long-term survival comparable to the general population in highly symptomatic patients with HOCM?

P
Population
178 highly symptomatic, consecutive patients with hypertrophic obstructive cardiomyopathy (HOCM), mean age 58 ± 12 years, 53% women. 87% had NYHA class ≥3 dyspnoea at baseline.
I
Intervention
Alcohol septal ablation (ASA)
C
Comparator
Age- and sex-comparable general population
O
Outcome
Long-term survival (all-cause mortality)hard clinical

Alcohol septal ablation in highly symptomatic patients with HOCM yields long-term survival rates comparable to the general population.

Cite This Study

Veselka et al. (2014) studied this question.

synapsesocial.com/papers/6a83db47403dcf0d873c2443https://doi.org/10.1093/eurheartj/eht495

Topics

Cardiac device therapyHypertrophic cardiomyopathy
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