August 22, 2017Experimental PhysiologyOpen Access

Central angiotensin‐(1–7) increases osmotic thirst

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Population

Male Wistar rats divided into three groups: control, 24 h of water deprivation, and 24 h of salt loading

Comparison

Intracerebroventricular injections of Ang- vs Vehicle

Design

Preclinical

Authors

RDRaoni Conceição Dos‐SantosTulane University LMLívia da Rocha Natalino MonteiroUniversidade Federal Rural do Rio de Janeiro BPBruno Paes‐LemeNational Institutes of Health

Discussion

Member takes

Implication

Suggests a novel regulatory role for angiotensin-(1-7) in hydromin.

Structured PICO

Population

Male Wistar rats divided into three groups: control, 24 h of water deprivation (WD), and 24 h of salt loading (SL; 1.8% NaCl)

Intervention

Intracerebroventricular (i.c.v.) injections of Ang-(1-7)

Comparator

Vehicle

Outcome

Water intake and plasma concentration of vasopressinsurrogate

Central administration of angiotensin-(1-7) increases thirst after osmotic stimuli, suggesting a novel role for this peptide in hydromineral homeostasis.

Cite This Study

Dos‐Santos et al. (2017) studied this question.

synapsesocial.com/papers/6a83de082c2cbb2cd7b0511f https://doi.org/10.1113/ep086417

View Full Paper

Ask AI

Bookmark

Central angiotensin‐(1–7) increases osmotic thirst

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Central angiotensin‐(1–7) increases osmotic thirst

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider