Why the study?
Does simvastatin 80 mg improve skin microvascular function compared to ezetimibe 10 mg plus simvastatin 10 mg in patients with dysglycaemia and coronary artery disease?
Population
36 patients with dysglycaemia and coronary artery disease (CAD)
Comparison
Simvastatin 80 mg daily for 6 weeks vs Ezetimibe 10 mg and simvastatin 10 mg daily for…
Design
RCT, randomized
Follow-up
6 weeks
Authors
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Lipid lowering improves microvascular function in dysglycaemic CAD; confirms benefit driven by LDL reduction rather than statin pleiotropy.
Does simvastatin 80 mg improve skin microvascular function compared to ezetimibe 10 mg plus simvastatin 10 mg in patients with dysglycaemia and coronary artery disease?
Lipid lowering improves microvascular function in patients with dysglycaemia and CAD, with the effect driven primarily by LDL reduction rather than statin pleiotropic effects.
Settergren et al. (2009) studied this question.
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