Why the study?
Autonomic neuropathy in type 2 diabetes mellitus was suspected to impact sweat gland innervation, prompting evaluation of galvanic skin resistance.
Does basal galvanic skin resistance differ between patients with type 2 diabetes mellitus with neuropathy and healthy individuals?
Does basal galvanic skin resistance differ between patients with type 2 diabetes mellitus with neuropathy and healthy individuals?
Basal galvanic skin resistance is elevated in patients with type 2 diabetes and neuropathy, reflecting autonomic nervous system impairment.
Suggests autonomic impairment in diabetic neuropathy; hypothesis-generating, needs prospective validation before clinical adoption.
Introduction: Stress and sedentary lifestyles frequently result in chronic health issues such as diabetes; a metabolic disorder that impacts the neural system as a result of changes in multiple metabolic pathways. Long-term diabetes mellitus causes neuropathy, which affects the autonomic nervous system. The study was initiated based on indications that sweat glands innervated by the autonomic nervous system would be impacted in individuals with type 2 diabetes mellitus who also had neuropathy symptoms. The purpose of this study was to examine galvanic skin resistance (GSR) in patients with type 2 diabetes mellitus and healthy individuals. Material & Methods: A total of 60 subjects between the ages of 25- 60 years were included in the study. 60 healthy individuals in the same age group with no history of diabetes mellitus and neuropathy served as controls, while/participants with diabetes mellitus and a history of neuropathic symptoms served as cases. Galvanic skin resistance (GSR) was recorded using Physio-Pac 4 channel digital polygraph at the department of medicine. All recordings were made between 10:00 a.m. and 12:00 p.m. in the supine position at room temperature. Result: Basal Galvanic skin resistance was higher in the diabetic patients.
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Prajapati et al. (2022) studied this question.
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