Key result
Patients with type 2 diabetes and HbA1c >10 exhibited significantly lower sural sensory nerve conduction velocity compared to those with HbA1c <10 (41.43 vs 50.19 m/sec, p<0.0001).
Why the study?
The study aimed to examine the impact of glycemic management on nerve function and clarify whether it acts as an independent risk factor for diabetic neuropathy regardless of diabetes duration.
Does poor glycemic control (HbA1c >10) worsen neurophysiological parameters in patients with type 2 diabetes compared to HbA1c <10?
Population
150 type 2 diabetic patients visiting the diabetic outpatient department
Comparison
HbA1c levels <10 vs HbA1c levels >10
Design
Cross-sectional study
Authors
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Poorer glycemic control was associated with more severe electrophysiological neuropathy; leaves open causal impact on progression independent of diabetes duration.
Cross-Sectional (n=150)
Does poor glycemic control (HbA1c >10) worsen neurophysiological parameters in patients with type 2 diabetes compared to HbA1c <10?
Absolute Event Rate: 41.43% vs 50.19%
p-value: p=<0.0001
Poor glycemic control (HbA1c >10) in type 2 diabetes is associated with significantly worse sensory and motor nerve conduction parameters, indicating a higher risk of diabetic neuropathy.
Muley et al. (2022) conducted a cross-sectional in Type 2 Diabetes Mellitus (n=150). Poor glycemic control (HbA1c > 10) vs. Better glycemic control (HbA1c < 10) was evaluated on Sural sensory nerve conduction velocity (SNCV) (p=<0.0001). Patients with type 2 diabetes and HbA1c >10 exhibited significantly lower sural sensory nerve conduction velocity compared to those with HbA1c <10 (41.43 vs 50.19 m/sec, p<0.0001).
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