Key result
Hyperglycemia in newly diagnosed type 1 diabetes is linked to ~82% tibial nerve conduction slowing.
Why the study?
The effects of hyperglycemia on nerve conduction and the significance of early electrophysiological diagnostics in newly diagnosed type 1 diabetes mellitus patients were not well established.
Does early neurophysiological evaluation detect nerve conduction abnormalities in newly diagnosed type 1 diabetes mellitus patients?
Population
85 newly diagnosed type 1 diabetes mellitus patients within first three months
Comparison
Neurophysiological evaluation including NCV and late responses
Design
Cross-sectional study
Authors
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May support early neurophysiological screening in new T1DM with hyperglycemia; leaves open causality and outcome impact.
Cross-Sectional (n=85)
Does early neurophysiological evaluation detect nerve conduction abnormalities in newly diagnosed type 1 diabetes mellitus patients?
Early neurophysiological evaluation, particularly F-wave latency measurement, is sensitive for detecting nerve conduction slowing in newly diagnosed type 1 diabetes mellitus patients with poor metabolic control.
Matanović et al. (2013) conducted a cross-sectional in Diabetes Mellitus type 1 (n=85). Hyperglycemia was evaluated on Nerve conduction velocities (NCV) and late responses (F-wave and H-reflex). Hyperglycemia in newly diagnosed type 1 diabetes was associated with nerve conduction velocity slowing in the tibial nerve (82.4%) and prolonged F-wave latency (72.9%).
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