Population
Weanling hamsters inoculated intraperitoneally at 3 or 9 days of age
Comparison
Antithymocyte serum (ATS) and measles virus vs Normal rabbit serum plus measles virus, or ATS…
Design
Preclinical
Follow-up
adult life
Authors
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Does not support late CNS sequelae in this immunosuppressed model; leaves open mechanisms of sustained antibody formation.
In hamsters, ATS treatment combined with measles virus infection can induce early CNS signs and sustained antibody formation, but does not lead to late CNS complications in adult life.
Cremer et al. (1977) studied this question.
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