Why the study?
Cardiomyopathy is a rare but serious side effect of clozapine that necessitates drug discontinuation.
This case report highlights a rare but serious instance of clozapine-induced cardiomyopathy, reinforcing the need for strict monitoring of patients on this medication.
May warrant cardiac monitoring in clozapine users; leaves open incidence and optimal surveillance in larger cohorts.
Clozapine is an antipsychotic medication prescribed for patients who do not respond to or cannot tolerate standard antipsychotic treatments. It is also used to manage psychosis associated with Parkinson's disease. As a high-risk drug, clozapine requires strict monitoring. A rare but serious side effect is cardiomyopathy, which necessitates discontinuation of the medication. This report presents the case of a 42-year-old male patient admitted with recurrent falls and urinary sepsis while on clozapine. He exhibited persistent tachycardia and drowsiness and was diagnosed with cardiomyopathy, likely induced by clozapine.
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Gourisaria et al. (2025) studied this question.
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