May 1, 2001Journal of Applied Physiology
Reflex control of the cutaneous circulation after acute and chronic local capsaicin
Why the study?
Does topical capsaicin alter the reflex cutaneous vasodilator response to hyperthermia in humans?
Population
Humans
Comparison
Acute low-dose topical capsaicin and chronic… vs Control skin sites
Design
Other
Authors
Discussion
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Member takes
Implication
Topical capsaicin does not alter reflex cutaneous vasodilation during hyperthermia; leaves open the role of capsaicin-sensitive afferents in thermoregulation.
Structured PICO
Does topical capsaicin alter the reflex cutaneous vasodilator response to hyperthermia in humans?
P
Population
Humans
I
Intervention
Acute low-dose topical capsaicin (0.025%) and chronic topical capsaicin (0.075% for 7 days)
C
Comparator
Control skin sites
O
Outcome
Reflex cutaneous vasodilator response to hyperthermia (maximum cutaneous vascular conductance, internal temperature thresholds, and sensitivity)surrogate
Local activity of capsaicin-sensitive afferents in the skin does not modify reflex cutaneous vasodilation during hyperthermia.
Cite This Study
Charkoudian et al. (2001) studied this question.