Why the study?
Does long-term antidepressant use increase the risk of type 2 diabetes mellitus in a general population?
Population
143,655 individuals from Taiwan's National Health Insurance Research Database
Comparison
Long-term antidepressant use (> 2 years) vs Nonusers of antidepressants
Design
Case-control
Authors
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May support glycemic monitoring in long-term users; leaves open causality and requires prospective confirmation.
Does long-term antidepressant use increase the risk of type 2 diabetes mellitus in a general population?
Long-term antidepressant use (>2 years) is associated with a 20% increased risk of developing type 2 diabetes mellitus, with a more pronounced risk in younger adults.
Wu et al. (2014) studied this question.
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