Clinical management of clopidogrel inefficiency by point of care platelet function testing and individual adjustment of anti-platelet therapy – initial experiences

Patients with insufficient inhibition of ADP-dependent platelet aggregation by clopidogrel after percutaneous coronary intervention, including a highlighted patient with recurrent acute myocardial infarction due to stent thrombosis following elective drug-eluting stent implantation.

Point of care platelet function testing (multiple electrode impedance) and individual adjustment of anti-platelet therapy (clopidogrel dose adjustment or switching to prasugrel).

Inhibition of ADP-dependent platelet aggregation.surrogate