Why the study?
Does in vitro bleeding time (IVBT) improve the detection of primary haemostasis disorders compared to in vivo bleeding time?
Population
Blood donors before and after ASA ingestion, patients with thrombocytopenia, and patients with congenital…
Comparison
In vitro bleeding time testing using Thrombostat… vs In vivo bleeding time (BT).
Design
Review
Authors
Loading...
IVBT with PFA-EPI may enhance von Willebrand syndrome detection; leaves open whether it supplants in vivo bleeding time pending prospective validation.
Does in vitro bleeding time (IVBT) improve the detection of primary haemostasis disorders compared to in vivo bleeding time?
In vitro bleeding time testing, particularly with PFA-100, offers superior sensitivity to traditional in vivo bleeding time for detecting von Willebrand syndrome and monitoring desmopressin therapy.
Weippert-Kretschmer et al. (1999) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: