Why the study?
Are measurements of CK-MB mass and activity concentrations comparable for the detection or exclusion of acute myocardial infarction in patients admitted to the cardiac-care unit?
Population
226 patients admitted to the cardiac-care unit (providing 1298 plasma samples)
Comparison
Measurement of CK-MB mass concentration using an… vs Measurement of CK-MB activity concentration…
Design
Cross-sectional
Authors
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High concordance supports interchangeable CK-MB assays in CCU; leaves open added diagnostic value versus contemporary troponin.
Are measurements of CK-MB mass and activity concentrations comparable for the detection or exclusion of acute myocardial infarction in patients admitted to the cardiac-care unit?
Measurements of CK-MB mass and activity concentrations using specific monoclonal antibodies are highly concordant and comparable for detecting or excluding acute myocardial infarction.
Eisenberg et al. (1989) studied this question.
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