Why the study?
How does column chromatography compare with immunoinhibition for the measurement of plasma CK-MB activity in patients admitted to the coronary care unit?
How does column chromatography compare with immunoinhibition for the measurement of plasma CK-MB activity in patients admitted to the coronary care unit?
Both column chromatography and immunoinhibition are acceptable methods for routine laboratory measurement of CK-MB in patients with suspected myocardial infarction.
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Both methods support resource-based selection for CK-MB; leaves open standardization needs in routine labs.
Two methods for the measurement of plasma creatine kinase MB (CK-MB) activity were compared for analytical performance, cost, practicality, and diagnostic correlation with clinical and electrocardiographic findings in patients admitted to the coronary care unit of a district general hospital. The methods were column chromatography and immunoinhibition. Both methods were found acceptable, and the method to be adopted would depend on the staff arrangements and resources available in the laboratory.
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Surtees et al. (1979) studied this question.
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