Key result
Each 10 mmHg higher systolic blood pressure was associated with an 18% (95% CI 9-27%) and 23% (95% CI 19-26%) greater risk for coronary heart disease among those with and without diabetes.
Why the study?
Is the association between systolic blood pressure and cardiovascular disease risk similar in individuals with and without diabetes?
Population
368,307 participants from 36 cohort studies in the Asia-Pacific region, 6.4% with diabetes.
Comparison
Systolic blood pressure level vs Lower systolic blood pressure levels
Design
Meta-analysis
Loading...
Supports similar relative CHD risk elevation with higher SBP regardless of diabetes; extends meta-analyses of observational data across glycemic strata.
Cohort (n=368,307)
Yes
Is the association between systolic blood pressure and cardiovascular disease risk similar in individuals with and without diabetes?
Hazard Ratio: 1.18 (95% CI 1.09–1.27)
Higher systolic blood pressure is associated with a similar relative increase in cardiovascular disease risk regardless of diabetes status.
A 2007 study conducted a cohort in Cardiovascular diseases (n=368,307). 10 mmHg higher systolic blood pressure vs. Lower systolic blood pressure was evaluated on Coronary heart disease (CHD) (HR 1.18, 95% CI 1.09-1.27). Each 10 mmHg higher systolic blood pressure was associated with an 18% (95% CI 9-27%) and 23% (95% CI 19-26%) greater risk for coronary heart disease among those with and without diabetes.