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April 1, 2003Journal of Hypertension

Blood pressure and cardiovascular disease in the Asia Pacific region

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Why the study?

Is lower systolic blood pressure associated with a reduced risk of stroke, ischaemic heart disease, and cardiovascular death in the Asia Pacific population?

Population

425,325 participants from 37 cohort studies in the Asia Pacific region

Design

Meta-analysis

Follow-up

over 3 million person-years

Discussion

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Overview

Supports lower SBP targets in younger Asia Pacific adults; extends log-linear risk reduction evidence to 115 mmHg in regional meta-analyses.

Structured PICO

Is lower systolic blood pressure associated with a reduced risk of stroke, ischaemic heart disease, and cardiovascular death in the Asia Pacific population?

P
Population
425,325 participants from 37 cohort studies in the Asia Pacific region (Australia, mainland China, Hong Kong, Japan, New Zealand, Singapore, South Korea, and Taiwan)
I
Intervention
Systolic blood pressure levels
O
Outcome
Stroke, ischaemic heart disease, total cardiovascular deathhard clinical

Lower systolic blood pressure is continuously associated with reduced risk of stroke and ischemic heart disease down to at least 115 mmHg across age groups in the Asia Pacific region.

Cite This Study

A 2003 study studied this question.

synapsesocial.com/papers/6a7ceceeff0bedc5b12fa70ahttps://doi.org/10.1097/00004872-200304000-00013

Topics

Hypertension managementWomen and heart disease
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Also Consider

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  1. 1Chinese Trial on Isolated Systolic Hypertension in the Elderly2000 · 286 citations
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  4. 4Measurement error, instrumental variables and corrections for attenuation with applications to meta‐analyses1994 · 90 citations
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