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July 29, 2005Future Oncology

Ang-1 promotes endothelial cell survival and tumor angiogenesis, whereas Ang-2 destabilizes vasculature leading to angiogenesis or apoptosis depending on VEGF presence, and Ang-3 displays antiangiogenic activity.

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QYQin YuJiangsu University

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Overview

Ang-Tie-2 modulation should not yet guide antiangiogenic cancer therapy; leaves open its clinical potential pending prospective trials.

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Cite This Study

Qin Yu (2005) studied this question.

synapsesocial.com/papers/6a8431fcac510c864ff2fff6https://doi.org/10.2217/14796694.1.4.475
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