September 1, 1987European Journal of Endocrinology
Atrial natriuretic polypeptide during exercise in healthy man
Why the study?
Does graded exercise increase plasma atrial natriuretic polypeptide levels in healthy men?
Structured PICO
Does graded exercise increase plasma atrial natriuretic polypeptide levels in healthy men?
P
Population
8 healthy men
I
Intervention
Two grades of exercise (20% and 40% of maximal oxygen uptake) performed in the supine position on a bicycle ergometer
C
Comparator
Baseline and lower intensity exercise (20% of maximal oxygen uptake)
O
Outcome
Plasma concentration of atrial natriuretic polypeptidesurrogate
Plasma concentration of atrial natriuretic polypeptide increases in response to exercise workload intensity, suggesting exercise is a useful test to evaluate ANP releasing function.
Authors
Discussion
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Implication
Supports graded exercise as ANP stimulus; leaves open diagnostic utility pending validation in disease.
Cite This Study
Saito et al. (1987) studied this question.