Population
Dogs with a working left ventricle preparation allowing isolated perfusion of coronary and systemic…
Comparison
Injection of catecholamines, sympathetic nerve… vs Baseline state or post-vagotomy state
Design
Preclinical
Authors
Loading...
Supports LV mechanoreceptor vagal reflex in animal models; leaves open relevance to human cardiovascular regulation or therapy.
Left ventricular mechanoreceptors mediate a vagal reflex that reduces peripheral resistance in response to increased myocardial contractility or stretch.
Fox et al. (1977) studied this question.
Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context: