Why the study?
Does intravenous infusion of β-lipoprotein-rich plasma improve glyceride transport in a patient with abetalipoproteinemia?
Population
11-year-old boy with abetalipoproteinemia (n=1)
Design
Case_report
Follow-up
more than six days
Authors
Loading...
β-lipoprotein infusion fails to restore glyceride transport in abetalipoproteinemia; indicates intrinsic cellular defect and leaves open other therapeutic targets.
Does intravenous infusion of β-lipoprotein-rich plasma improve glyceride transport in a patient with abetalipoproteinemia?
Providing β-lipoprotein to a patient with abetalipoproteinemia does not reverse defects in glyceride transport, indicating the defect is not simply due to lack of circulating β-lipoprotein.
Lees et al. (1969) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: