December 1, 1982Journal of Lipid ResearchOpen Access

Abnormal high density lipoproteins of abetalipoproteinemia: relevance to normal HDL metabolism

View Full Paper

Ask AI

Bookmark

Population

Subjects with abetalipoproteinemia (n=3) and normal subjects (n=3)

Design

Case-control

Authors

RDRichard J. DeckelbaumColumbia University SES EisenbergHadassah Medical Center YOY OschryTel Aviv University

Discussion

Member takes

Implication

Characterizes HDL2 predominance and enlargement in abetalipoproteinemia; leaves open whether these particles alter cardiovascular risk or guide therapy.

Structured PICO

Population

Subjects with abetalipoproteinemia (n=3) and normal subjects (n=3)

Comparator

Normal subjects

Outcome

HDL subfraction characteristics (mass, size, density, apoprotein E content, cholesteryl ester content)surrogate

The absence of cholesteryl ester transfer to triglyceride-rich lipoproteins in abetalipoproteinemia leads to the accumulation of abnormally large, cholesteryl ester-rich HDL particles.

Cite This Study

Deckelbaum et al. (1982) studied this question.

synapsesocial.com/papers/6a8445a6da9d2319e77bfd0c https://doi.org/10.1016/s0022-2275(20)38032-9

View Full Paper

Ask AI

Bookmark

Implication

Characterizes HDL2 predominance and enlargement in abetalipoproteinemia; leaves open whether these particles alter cardiovascular risk or guide therapy.

Abnormal high density lipoproteins of abetalipoproteinemia: relevance to normal HDL metabolism

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Abnormal high density lipoproteins of abetalipoproteinemia: relevance to normal HDL metabolism

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider