Population
Bovine pulmonary arterial endothelial cells (BPAEC)
Comparison
Recombinant human erythropoietin 3.3 U/ml, with… vs Control (untreated cells)
Design
Preclinical
Follow-up
4 hours
Authors
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Should not yet change EPO use; leaves open calcium-ET-1 mechanisms in human pulmonary endothelium.
Erythropoietin stimulates endothelin-1 synthesis and release in pulmonary arterial endothelial cells via calcium signaling.
Carlini et al. (1995) studied this question.
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