Key result
Progression of carotid stenosis was a highly significant predictor of the composite outcome of TIA and CVA (RR 1.68; P<.001) and of CVA alone (RR 1.78; P<.001).
Why the study?
Does the progression of carotid stenosis predict ischemic neurological outcomes better than a single baseline measurement in asymptomatic patients?
Population
1004 asymptomatic patients followed by duplex ultrasonographic scanning at a Veterans Affairs Medical Center…
Comparison
Progression of carotid stenosis assessed by… vs Single baseline measurement of carotid stenosis
Design
Cohort
Authors
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May support serial duplex over single baseline measurement in asymptomatic patients; hypothesis-generating for intervention thresholds.
Cohort (n=1,004)
No
Does the progression of carotid stenosis predict ischemic neurological outcomes better than a single baseline measurement in asymptomatic patients?
Relative Risk: 1.68
p-value: p=<.001
Progression of carotid stenosis is a better predictor of ischemic neurological events than a single baseline measurement, highlighting the value of serial duplex scanning in asymptomatic patients.
Bertges et al. (2003) conducted a cohort in Asymptomatic carotid stenosis (n=1,004). Progression of carotid stenosis vs. Baseline carotid stenosis was evaluated on Composite outcome of ipsilateral transient ischemic attack (TIA) and cerebrovascular accident (CVA) (RR 1.68, p=<.001). Progression of carotid stenosis was a highly significant predictor of the composite outcome of TIA and CVA (RR 1.68; P<.001) and of CVA alone (RR 1.78; P<.001).
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