Population
Porcine cell lines, primary swine testicle cells, and 3 5-day-old piglets
Comparison
Infection with Classical Swine Fever Virus… vs Mock-infected cells, or cells infected with…
Design
Preclinical
Authors
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In vitro CSFV apoptosis mechanism via DI particles warrants caution extrapolating to swine; leaves open in vivo relevance for pathogenesis.
The cytopathogenicity of CSFV strain WB82 is caused by apoptosis mediated by defective interfering particles containing subgenomic RNA.
Aoki et al. (2001) studied this question.
Synapse has enriched 3 closely related papers on similar clinical questions. Consider them for comparative context: