Key result
Inhibition of the renin-angiotensin system improves insulin sensitivity and decreases the incidence of Type 2 Diabetes Mellitus in patients with hypertension and metabolic syndrome.
Why the study?
Do drugs targeting the renin-angiotensin-aldosterone system improve glucose metabolism and prevent type 2 diabetes in patients with hypertension and metabolic syndrome?
Population
Patients with hypertension and metabolic syndrome (insulin resistant patients)
Design
Review
Authors
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May support RAAS inhibition for diabetes prevention in hypertension; leaves open confirmation in prospective RCTs.
Do drugs targeting the renin-angiotensin-aldosterone system improve glucose metabolism and prevent type 2 diabetes in patients with hypertension and metabolic syndrome?
Inhibition of the renin-angiotensin system improves insulin sensitivity and may represent a strategy to prevent type 2 diabetes in patients with hypertension and metabolic syndrome.
Muscogiuri et al. (2008) conducted a review in Essential hypertension, insulin resistance, and Type 2 Diabetes Mellitus. Inhibition of the renin-angiotensin system was evaluated. Inhibition of the renin-angiotensin system improves insulin sensitivity and decreases the incidence of Type 2 Diabetes Mellitus in patients with hypertension and metabolic syndrome.
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