Key result
Bioresorbable scaffolds offer theoretical advantages over metallic drug-eluting stents, but current evidence shows comparable short-term outcomes with concerns regarding higher rates of device thrombosis.
Why the study?
Do bioresorbable scaffolds improve clinical outcomes compared to metallic drug-eluting stents in patients with obstructive coronary artery disease?
Do bioresorbable scaffolds improve clinical outcomes compared to metallic drug-eluting stents in patients with obstructive coronary artery disease?
While bioresorbable scaffolds present an attractive concept for coronary revascularization, their superiority over second-generation drug-eluting stents remains unproven, and optimal implantation techniques are crucial to mitigate thrombosis risks.
Should not yet change practice for coronary revascularization; leaves open need for long-term RCTs with optimized techniques.
In the field of percutaneous coronary intervention, the evolution of coronary metal stents has been well established for the past three decades, but research on bioresorbable scaffolds has only gained momentum in the recent past. Although second-generation drug-eluting metal stents are the gold standard for the treatment of obstructive coronary artery disease, a few drawbacks exist. The development of bioresorbable scaffolds is an attempt to overcome the limitations of metal stents. This review highlights the rationale for the bioresorbable scaffold, its properties and potential applications. It also focuses on the current evidence and concerns regarding the application of the bioresorbable scaffold in day-to-day practice.
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Tan et al. (2016) conducted a review in Coronary artery disease. Bioresorbable scaffolds vs. Metallic drug-eluting stents was evaluated. Bioresorbable scaffolds offer theoretical advantages over metallic drug-eluting stents, but current evidence shows comparable short-term outcomes with concerns regarding higher rates of device thrombosis.
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