Key result
Obesity impaired vascular reactivity in older adults, with a lower absolute change in calf blood flow from rest to post-occlusion in obese (1.93 %/min) versus normal weight individuals (5.21 %/min).
Why the study?
Does obesity impair vascular reactivity in older adults without overt cardiovascular disease?
Cross-Sectional (n=87)
No
Does obesity impair vascular reactivity in older adults without overt cardiovascular disease?
Absolute Event Rate: 1.93% vs 5.21%
p-value: p=0.001
Obesity and abdominal adiposity are associated with impaired vascular reactivity in older adults, independent of conventional cardiovascular risk factors.
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Obesity was associated with impaired vascular reactivity in older adults without overt CVD; leaves open causality and intervention effects in prospective studies.
Acree et al. (2007) conducted a cross-sectional in Obesity (n=87). Obesity vs. Normal weight was evaluated on Absolute change in calf blood flow from rest to post-occlusive reactive hyperemia (p=0.001). Obesity impaired vascular reactivity in older adults, with a lower absolute change in calf blood flow from rest to post-occlusion in obese (1.93 %/min) versus normal weight individuals (5.21 %/min).
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