Why the study?
Does a high-fat meal alter postprandial vascular reactivity differently in obese compared to normal weight young adults?
Population
22 young adults, comprising 11 obese and 11 normal weight age- and sex-matched controls.
Comparison
High-fat meal vs Normal weight controls and baseline pre-meal state
Design
Cohort
Follow-up
3 hours
Authors
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Does not support differential postprandial endothelial impairment by weight status; leaves open its contribution to obesity-related CV risk.
Does a high-fat meal alter postprandial vascular reactivity differently in obese compared to normal weight young adults?
Vascular responses to a high-fat meal are similar in obese and normal weight young adults, suggesting that exaggerated postprandial vascular reactivity is unlikely to be a major driver of obesity-related cardiovascular risk.
Ayer et al. (2009) studied this question.
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