Key result
Verapamil showed no difference compared to digoxin for heart rate control in new-onset atrial fibrillation, achieving best rate control in 46.7% vs 36.7% of patients, respectively.
Why the study?
Does intravenous verapamil improve acute heart rate control compared to intravenous digoxin in patients with new-onset atrial fibrillation and rapid ventricular response?
Population
60 patients with new-onset atrial fibrillation and rapid ventricular response presenting to an emergency…
Comparison
Intravenous verapamil, initial dose of 2.5 mg… vs Intravenous digoxin, initial dose of 0.5 mg…
Design
Cohort
Follow-up
12 hours
Authors
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No difference observed with verapamil versus digoxin for acute rate control; should not yet change practice and leaves open need for RCTs.
Observational (n=60)
No
Does intravenous verapamil improve acute heart rate control compared to intravenous digoxin in patients with new-onset atrial fibrillation and rapid ventricular response?
Absolute Event Rate: 46.7% vs 36.7%
p-value: p=0.002
Intravenous verapamil and digoxin are equally effective for achieving acute heart rate control in emergency department patients with new-onset atrial fibrillation.
Moghadam et al. (2012) conducted an observational in Atrial fibrillation (n=60). Verapamil vs. Digoxin was evaluated on Heart rate control (p=0.002). Verapamil showed no difference compared to digoxin for heart rate control in new-onset atrial fibrillation, achieving best rate control in 46.7% vs 36.7% of patients, respectively.
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