Key result
This document is a journal masthead and does not contain clinical study results.
Why the study?
Do von Willebrand factor abnormalities cause clinical bleeding in patients with severe aortic valve stenosis?
Population
41 consecutive patients with severe aortic valve stenosis undergoing valve replacement
Design
Cohort
Follow-up
up to six months after surgery
Authors
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Acquired vWF abnormalities in severe AS do not typically cause bleeding; leaves open whether targeted testing alters pre-replacement management.
Do von Willebrand factor abnormalities cause clinical bleeding in patients with severe aortic valve stenosis?
While acquired von Willebrand syndrome is common in severe aortic stenosis (especially rheumatic cases), the loss of large multimers does not typically cause clinical bleeding and corrects rapidly after valve replacement.
Sponga et al. (2011) studied aortic valve stenosis. This document is a journal masthead and does not contain clinical study results.
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