Key result
Postnatal development in rats was associated with increased cell capacitance, decreased input resistance, and larger action potential overshoots in intrinsic cardiac ganglion neurons.
Population
Rat intrinsic cardiac ganglion neurons from excised right atrial ganglion plexus across postnatal…
Comparison
Postnatal development vs Comparison across developmental stages
Design
Preclinical
Authors
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May refine models of postnatal autonomic maturation; leaves open translation to human cardiac electrophysiology or disease.
Postnatal development in rats is associated with significant maturation of the intrinsic electrical properties of intracardiac ganglion neurons, indicating increased complexity in parasympathetic cardiac regulation.
Rimmer et al. (2006) studied Normal postnatal development. Postnatal development vs. Neonatal stage was evaluated on Electrophysiological properties and synaptic responses. Postnatal development in rats was associated with increased cell capacitance, decreased input resistance, and larger action potential overshoots in intrinsic cardiac ganglion neurons.
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