Key result
Electrical stimulation of the vagus nerve in neonatal rat cardiac ganglia evoked fast excitatory postsynaptic potentials, suggesting a role for noncholinergic transmission in regulating the heartbeat.
Population
Neonatal rat cardiac ganglion in situ
Design
Preclinical
Authors
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Neonatal rat findings offer no clinical guidance for vagal stimulation; leaves open noncholinergic transmission in adult mammalian or human cardiac ganglia.
The study demonstrates the presence of noncholinergic transmission in neonatal rat cardiac ganglia, suggesting its role in regulating the mammalian heartbeat.
Seabrook et al. (1990) studied Neonatal rat cardiac ganglion. Electrical stimulation of the vagus nerve was evaluated on Electrophysiological and histochemical characteristics. Electrical stimulation of the vagus nerve in neonatal rat cardiac ganglia evoked fast excitatory postsynaptic potentials, suggesting a role for noncholinergic transmission in regulating the heartbeat.
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