Key result
Real time three-dimensional echocardiography (RT3DE) is a novel noninvasive imaging modality that can quantify left ventricular dyssynchrony and evaluate or predict the response to cardiac resynchronization therapy.
Why the study?
Does real time three-dimensional echocardiography (RT3DE) accurately assess left ventricular dyssynchrony and predict response to cardiac resynchronization therapy in patients with symptomatic heart failure?
Does real time three-dimensional echocardiography (RT3DE) accurately assess left ventricular dyssynchrony and predict response to cardiac resynchronization therapy in patients with symptomatic heart failure?
Real time three-dimensional echocardiography (RT3DE) is a novel noninvasive imaging modality that can quantify left ventricular dyssynchrony and may improve patient selection for cardiac resynchronization therapy.
May refine CRT selection in HF; hypothesis-generating pending prospective validation.
Left ventricular (LV) mechanical dyssynchrony is an important prognostic marker for higher morbidity and mortality in patients with symptomatic heart failure. However, the response rate to resynchronization varies among patients meeting current guidelines for Cardiac resynchronization therapy (CRT). Two-dimensional echocardiography and Doppler-based techniques have shown variable results in the assessment of LV dyssynchrony. There is an obvious need for a noninvasive tool that can reliably measure LV dyssynchrony. Accurate prediction of response to CRT will improve patient selection for such therapy. Real time three-dimensional echocardiography (RT3DE) is a novel noninvasive imaging modality that has been recently used in quantitative evaluation of global and regional LV function. A number of published studies have described the use of RT3DE in the measurement of LV dyssynchrony in patients with normal or reduced LV function. The systolic dyssynchrony index derived from RT3DE has been used to quantify LV dysynchrony and to evaluate and predict the response to CRT. This review will discuss the recently published data regarding the role of RT3DE in CRT.
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Wang et al. (2012) conducted a review in Symptomatic heart failure with left ventricular mechanical dyssynchrony. Real time three-dimensional echocardiography (RT3DE) was evaluated. Real time three-dimensional echocardiography (RT3DE) is a novel noninvasive imaging modality that can quantify left ventricular dyssynchrony and evaluate or predict the response to cardiac resynchronization therapy.