Why the study?
Does ACE inhibition alter the renal and systemic responses to low-level electrical stimulation of the renal nerves in anesthetized rabbits?
Population
Pentobarbitone-anesthetized rabbits
Comparison
Low-level electrical stimulation to the left… vs Low-level electrical stimulation in the absence…
Design
Preclinical
Follow-up
180 minutes
Authors
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ACE inhibition abolishes renal nerve effects in rabbits; hypothesis-generating for angiotensin II mediation, with no clinical implications yet.
Does ACE inhibition alter the renal and systemic responses to low-level electrical stimulation of the renal nerves in anesthetized rabbits?
The antidiuresis and antinatriuresis observed during renal nerve activation are partially mediated by a neurally induced increase in systemic angiotensin II.
Fevre et al. (2003) studied this question.
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