The role of the autonomic innervation in the control of glucagon release during hypoglycaemia in the calf
Population
Calves 3-6 weeks after birth
Comparison
Insulin-induced hypoglycemia combined with… vs Normal conscious calves or baseline state
Design
Preclinical
Follow-up
Acute (within 30 min)
Authors
Discussion
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Member takes
Implication
Supports parasympathetic role in calf glucagon secretion; leaves open translation to other species or clinical settings.
Structured PICO
P
Population
Calves 3-6 weeks after birth
I
Intervention
Insulin-induced hypoglycemia (0.1 u./kg) combined with autonomic manipulations (atropine, splanchnic nerve section, or vagal stimulation)
C
Comparator
Normal conscious calves or baseline state
O
Outcome
Plasma glucagon concentrationsurrogate
Parasympathetic efferent activity is likely implicated in the glucagon response to physiological changes in plasma glucose concentration in calves.
Cite This Study
Bloom et al. (1974) studied this question.