Heritability of Early Repolarization
Population
1,877 individuals from 505 white nuclear families representative of the British general population
Design
Cohort
Authors
Discussion
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Member takes
Implication
Supports genetic studies of early repolarization; should not yet alter clinical ECG interpretation or family screening.
Structured PICO
P
Population
1,877 individuals from 505 white nuclear families representative of the British general population
O
Outcome
Heritability of early repolarization (defined as J-point elevation of ≥0.1 mV in at least 2 adjacent inferior or anterolateral leads on 12-lead ECG)surrogate
Early repolarization is a heritable ECG phenotype, with offspring of affected parents having a significantly increased risk of presenting with the pattern.
Cite This Study
Reinhard et al. (2011) studied this question.