Why the study?
Does a brachial-ankle pulse wave velocity cutoff of ≥18.3 m/s predict the development of cardiovascular disease in patients with hypertension?
Does a brachial-ankle pulse wave velocity cutoff of ≥18.3 m/s predict the development of cardiovascular disease in patients with hypertension?
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A brachial-ankle pulse wave velocity of ≥18.3 m/s is an independent predictor of future cardiovascular disease in patients with hypertension and may serve as a useful marker of subclinical organ damage.
BACKGROUND: The optimal cutoff values of the brachial-ankle pulse wave velocity (baPWV) for predicting cardiovascular disease (CVD) were examined in patients with hypertension. METHODS AND RESULTS: A total of 7,656 participants were followed prospectively. The hazard ratio for the development of CVD increased significantly as the baPWV increased, independent of conventional risk factors. The receiver-operating characteristic curve analysis showed that the optimal cutoff values for predicting CVD was 18.3 m/s. This cutoff value significantly predicted THE incidence of CVD. CONCLUSIONS: The present analysis suggests that the optimal cutoff value for CVD in patients with hypertension is 18.3 m/s.
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Ohkuma et al. (2017) studied this question.
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