Reaction of a variety of 1,2-epoxyalkanes with 2.5 equiv. of bulky metal amide—lithium 2,2,6,6-tetramethylpiperidide—affords the corresponding aldehydes exclusively in high yields; this is the first example of base-promoted isomerization of monosubstituted epoxides to aldehydes.
No takes yet. Share an insight, caveat, or question.
Yanagisawa et al. (1994) studied this question.
Synapse has enriched 5 related papers. Consider them for comparative context: