Key Points
- To describe the clinical presentation, pathologic correlation, and multimodality imaging findings associated with rare primary and secondary breast angiosarcomas.
- Reviewed clinical features and pathology profiles of primary and secondary breast angiosarcoma cases.
- Evaluated the performance of standard breast imaging techniques and dynamic contrast-enhanced MRI for assessing tumor margins and malignancy grade.
- Both primary and postirradiation angiosarcomas typically present with bruiselike skin discoloration, a benign appearance that frequently delays clinical diagnosis.
- Conventional imaging features are nonspecific, but MRI demonstrates high diagnostic utility for delineating lesion extent via rapid contrast enhancement and washout kinetics in high-grade malignancies.
- Reports of secondary breast angiosarcoma have increased concurrently with the broader clinical adoption of post-lumpectomy radiation in breast conservation therapy.
Structured PICO
PPopulationPatients with primary and secondary angiosarcomas of the breast
MRI is useful for determining the extent of breast angiosarcomas, which can present with nonspecific imaging findings and bruiselike skin discoloration.